Bed Sore Studies
Although a completely preventable condition, bed sores still require a lengthy and painful treatment process. However, academics are conducting current research to increase healing times and decrease the reappearance of healed sores.A Pilot Study of the Envision Surface
Sponsored by Hill-Rom, this 2007 study examines the safety and effectiveness of the Envision, a surface designed to expedite pressure ulcer healing through five key factors: shear, friction, immobility, microclimate management, and pressure. Researchers chose 30 participants with pressure ulcers or at risk of pressure ulcers to rest on Envision surfaces.
According to the findings, researchers discovered that:
- Patients with pressure ulcers experienced a significant decrease while laying on Envision surfaces.
- Ulcer volume decreased by an average of 41%
- Ulcer area decreased by an average of 5%
- No new pressure ulcers developed
Hematopoietic Stem Cell Therapy in Chronic Wounds Using a Pressure Sore Model
University Hospital in Basel, Switzerland sponsored this study examining the potential effects of stem cell treatment on pressure ulcers to accelerate and enhance wound healing. Researchers studied 5 patients with pressure ulcers in a pilot study and reevaluated their conditions through this study design:
- First, researchers performed a surgical intervention to debride the pressure sore and isolate stem cells.
- Next, researchers gave participants stem cell therapy on one-half of their wound surfaces and a control saline solution on the other half.
- Then, researchers performed a second surgery that removed the wound.
- Finally, researchers monitored wound healing through laser imaging, clinical treatment, and other methods.
The researchers have not yet reported their findings for this study.Interdisciplinary Pressure Management & Mobility Program as an Alternative to Usual Care: A Pilot Study (WOUND)
The University of Western Ontario, Canada, sponsored this study along with a collaborator, the Ontario Neurotrauma Foundation. The study examined alternative pressure ulcer treatments for people suffering from spinal cord injuries (SCI), which increase a person's risk of developing pressure ulcers. According to the research, nearly 82% of people with SCIs develop pressure ulcers. The researchers tested the effectiveness of an individualized, community-based pressure management program as compared to normal bed rest treatment.
The individualized treatment program included the following components:
- An in-depth home assessment by a registered therapist
- An analysis of home surfaces
- Identification of equipment and services needed to reduce pressure and friction, and improve patient mobility
- Development of a customized, safe mobility program to increase strength, independence, and balance
The Department of Veterans' Affairs sponsored this study, which examined the effects of the man-made steroid oxandrolone on pressure ulcer healing in 779 veterans with bed sores. The participants went through a round of standard bedsore treatment and those with unhealed sores underwent additional treatment. One group received a placebo and the other received a daily dose of 20 mg of oxandrolone.
The study found that:
- Oxandrolone has little potential impact on pressure ulcer healing rates.
- 24% of patients in oxandrolone group saw healed bed sores.
- 17% of patients with oxandrolone maintained healed ulcers after the study.
- 15% of the placebo group maintained healed bed sores.
This study, sponsored by Hill-Rom, examined pressure ulcer rates and change in existing sores for patients placed on standard ICU beds and a specialized bed known as TC500. Researchers studied 52 participants placed on the different beds receiving standard prevention care and daily skin assessments.Study of Thymosin Beta 4 in Patients With Pressure Ulcers
A study sponsored by RegeneRx Biopharmaceuticals Inc. examined the effectiveness of Thymosin Beta 4, a naturally occurring protein in the human body. The researchers applied a synthetic version of this protein topically to the participants' skin. The researchers examined the effectiveness of this substance in reducing pressure ulcers in 72 participants. One-half of the participants received a placebo and one-half received Thymosin Beta 4 at three doses.The Use of Specialized Amino Acid Mixture in Pressure Ulcer Wound Healing Rates - A Placebo Controlled Trial
Sponsored by Changi General Hospital, in collaboration with Abbott, this study examined the effects of a specialized mixture for treating severe pressure ulcers. The amino acid mixture contained the following substances:
- 7 grams of Arginine
- 7 grams of Glutamine
- 1.2 grams of beta-hydroxy-beta-methylbutyrate (HMB)
26 participants participated in this study, all of which had non-healing pressure ulcers at stage II or higher. Half of the group received a placebo and the other half received the amino acid mixture as a dietary supplement. The study looked for three outcome measures:
- Percentage of viable (healthy) and non-viable (dead or unhealthy) tissue
- Percentage of wound area after week 1
- Percentage of wound area after week 2
The study found that:
- Patients receiving the amino acid mixture had 43.06% of viable tissues, compared to 25.94% of placebo patients.
- Patients receiving the amino acid mixture saw a 15.37% reduction in wound area after week 1.
- Patients receiving the amino acid mixture saw a 27.5% reduction in wound area after week 2.
Do you have a loved one suffering from pressure ulcers because of nursing home neglect? Contact Nursing Home Law Center LLC to discuss your case and to receive a free evaluation today.
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